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Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes

Adipocytes support key metabolic and endocrine functions of adipose tissue. Lipid is stored in two major classes of depots, namely visceral adipose (VA) and subcutaneous adipose (SA) depots. Increased visceral adiposity is associated with adverse health outcomes, whereas the impact of SA tissue is r...

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Detalles Bibliográficos
Autores principales: Bradford, Stephen T., Nair, Shalima S., Statham, Aaron L., van Dijk, Susan J., Peters, Timothy J., Anwar, Firoz, French, Hugh J., von Martels, Julius Z. H., Sutcliffe, Brodie, Maddugoda, Madhavi P., Peranec, Michelle, Varinli, Hilal, Arnoldy, Rosanna, Buckley, Michael, Ross, Jason P., Zotenko, Elena, Song, Jenny Z., Stirzaker, Clare, Bauer, Denis C., Qu, Wenjia, Swarbrick, Michael M., Lutgers, Helen L., Lord, Reginald V., Samaras, Katherine, Molloy, Peter L., Clark, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606599/
https://www.ncbi.nlm.nih.gov/pubmed/31266983
http://dx.doi.org/10.1038/s41598-019-45777-w