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Protective effects of delayed intraventricular TLR7 agonist administration on cerebral white and gray matter following asphyxia in the preterm fetal sheep
Preterm brain injury is highly associated with inflammation, which is likely related in part to sterile responses to hypoxia-ischemia. We have recently shown that neuroprotection with inflammatory pre-conditioning in the immature brain is associated with induction of toll-like receptor 7 (TLR7). We...
Autores principales: | Cho, Kenta H. T., Wassink, Guido, Galinsky, Robert, Xu, Bing, Mathai, Sam, Dhillon, Simerdeep K., van den Heuij, Lotte G., Davidson, Joanne O., Weaver-Mikaere, Luke, Bennet, Laura, Gunn, Alistair J., Fraser, Mhoyra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606639/ https://www.ncbi.nlm.nih.gov/pubmed/31267031 http://dx.doi.org/10.1038/s41598-019-45872-y |
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