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Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN

Granzyme A (GzmA), together with perforin, are well-known for their cytotoxic activity against tumor or virus-infected cells. In addition to this cytotoxic function, GzmA stimulates several immune cell types and induces inflammation in the absence of perforin, however, its effect on the dendritic ce...

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Detalles Bibliográficos
Autores principales:	Shimizu, Kanako, Yamasaki, Satoru, Sakurai, Maki, Yumoto, Noriko, Ikeda, Mariko, Mishima-Tsumagari, Chiemi, Kukimoto-Niino, Mutsuko, Watanabe, Takashi, Kawamura, Masami, Shirouzu, Mikako, Fujii, Shin-ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606709/ https://www.ncbi.nlm.nih.gov/pubmed/31293597 http://dx.doi.org/10.3389/fimmu.2019.01450

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