Cargando…
Targeting GABA(A)R-Associated Proteins: New Modulators, Labels and Concepts
γ-aminobutyric acid type A receptors (GABA(A)Rs) are the major mediators of synaptic inhibition in the brain. Aberrant GABA(A)R activity or regulation is observed in various neurodevelopmental disorders, neurodegenerative diseases and mental illnesses, including epilepsy, Alzheimer’s and schizophren...
Autores principales: | Khayenko, Vladimir, Maric, Hans Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606717/ https://www.ncbi.nlm.nih.gov/pubmed/31293385 http://dx.doi.org/10.3389/fnmol.2019.00162 |
Ejemplares similares
-
Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype
por: Makbul, Cihan, et al.
Publicado: (2021) -
Low-cost synthesis of peptide libraries and their use for binding studies via temperature-related intensity change
por: Schulte, Clemens, et al.
Publicado: (2021) -
Limitations of Current GABA Agonists in Neonatal Seizures: Toward GABA Modulation Via the Targeting of Neuronal Cl(−) Transport
por: Khanna, Arjun, et al.
Publicado: (2013) -
High-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale
por: Schulte, Clemens, et al.
Publicado: (2020) -
GABA Not Only a Neurotransmitter: Osmotic Regulation by GABA(A)R Signaling
por: Cesetti, Tiziana, et al.
Publicado: (2012)