Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation

BACKGROUND: A positive energy balance promotes white adipose tissue (WAT) expansion which is characterized by activation of a repertoire of events including hypoxia, inflammation and extracellular matrix remodelling. The transmembrane glycoprotein CD248 has been implicated in all these processes in...

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Detalles Bibliográficos
Autores principales: Petrus, Paul, Fernandez, Tara L., Kwon, Michelle M., Huang, Jenny L., Lei, Victor, Safikhan, Nooshin Seyed, Karunakaran, Subashini, O'Shannessy, Daniel J., Zheng, Xiaowei, Catrina, Sergiu-Bogdan, Albone, Earl, Laine, Jukka, Virtanen, Kirsi, Clee, Susanne M., Kieffer, Timothy J., Noll, Christophe, Carpentier, André C., Johnson, James D., Rydén, Mikael, Conway, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606747/
https://www.ncbi.nlm.nih.gov/pubmed/31221584
http://dx.doi.org/10.1016/j.ebiom.2019.05.057

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