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2-BFI Provides Neuroprotection Against Inflammation and Necroptosis in a Rat Model of Traumatic Brain Injury

Inflammation and programmed necrosis (necroptosis) are the two hallmark pathological changes after traumatic brain injury (TBI) that contribute to aggravated brain damage. 2-(2-Benzofuranyl)-2-imidazoline (2-BFI) has been shown to exert both anti-inflammatory and programmed cell death effects. There...

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Detalles Bibliográficos
Autores principales: Ni, Haibo, Rui, Qin, Lin, Xiaolong, Li, Di, Liu, Huixiang, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606784/
https://www.ncbi.nlm.nih.gov/pubmed/31293382
http://dx.doi.org/10.3389/fnins.2019.00674