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Zika Virus-Immune Plasmas from Symptomatic and Asymptomatic Individuals Enhance Zika Pathogenesis in Adult and Pregnant Mice

Preexisting immunity against dengue virus or West Nile virus was previously reported to mediate antibody-dependent enhancement (ADE) of Zika virus (ZIKV) infection in a mouse model. We show here that ZIKV-immune plasma samples from both symptomatic and asymptomatic individuals mediated ZIKV ADE of i...

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Detalles Bibliográficos
Autores principales: Shim, Byoung-Shik, Kwon, Young-Chan, Ricciardi, Michael J., Stone, Mars, Otsuka, Yuka, Berri, Fatma, Kwal, Jaclyn M., Magnani, Diogo M., Jackson, Cody B., Richard, Audrey S., Norris, Philip, Busch, Michael, Curry, Christine L., Farzan, Michael, Watkins, David, Choe, Hyeryun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606798/
https://www.ncbi.nlm.nih.gov/pubmed/31266863
http://dx.doi.org/10.1128/mBio.00758-19