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The Symmetrical Wave Pattern of Base-Pair Substitution Rates across the Escherichia coli Chromosome Has Multiple Causes

Mutation accumulation experiments followed by whole-genome sequencing have revealed that, for several bacterial species, the rate of base-pair substitutions (BPSs) is not constant across the chromosome but varies in a wave-like pattern that is symmetrical about the origin of replication. The experim...

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Detalles Bibliográficos
Autores principales: Niccum, Brittany A., Lee, Heewook, MohammedIsmail, Wazim, Tang, Haixu, Foster, Patricia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606806/
https://www.ncbi.nlm.nih.gov/pubmed/31266871
http://dx.doi.org/10.1128/mBio.01226-19