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Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIV(smm/mac) Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization
As a consequence of their independent evolutionary origins in apes and Old World monkeys, human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency viruses of the SIV(smm/mac) lineage express phylogenetically and antigenically distinct envelope glycoproteins. Thus, HIV-1 Env-specific a...
Autores principales: | von Bredow, Benjamin, Andrabi, Raiees, Grunst, Michael, Grandea, Andres G., Le, Khoa, Song, Ge, Berndsen, Zachary T., Porter, Katelyn, Pallesen, Jesper, Ward, Andrew B., Burton, Dennis R., Evans, David T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606807/ https://www.ncbi.nlm.nih.gov/pubmed/31266872 http://dx.doi.org/10.1128/mBio.01255-19 |
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