Impact of NR1I2, adenosine triphosphate–binding cassette transporters genetic polymorphisms on the pharmacokinetics of ginsenoside compound K in healthy Chinese volunteers

BACKGROUND: Ginsenoside compound K (CK) is a promising drug candidate for rheumatoid arthritis. This study examined the impact of polymorphisms in NR1I2, adenosine triphosphate–binding cassette (ABC) transporter genes on the pharmacokinetics of CK in healthy Chinese individuals. METHODS: Forty-two t...

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Detalles Bibliográficos
Autores principales: Zhou, Luping, Chen, Lulu, Wang, Yaqin, Huang, Jie, Yang, Guoping, Tan, Zhirong, Wang, Yicheng, Liao, Jianwei, Zhou, Gan, Hu, Kai, Li, Zhenyu, Ouyang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606825/
https://www.ncbi.nlm.nih.gov/pubmed/31308818
http://dx.doi.org/10.1016/j.jgr.2018.04.003

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