Revisiting gametocyte biology in malaria parasites

Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito vector. They are present at low levels in blood circulation and significant knowledge gaps exist in their biology. Recent reductions in the global malaria burden have brought the possibility of elimination an...

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Detalles Bibliográficos
Autores principales: Ngotho, Priscilla, Soares, Alexandra Blancke, Hentzschel, Franziska, Achcar, Fiona, Bertuccini, Lucia, Marti, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606849/
https://www.ncbi.nlm.nih.gov/pubmed/31220244
http://dx.doi.org/10.1093/femsre/fuz010
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author Ngotho, Priscilla
Soares, Alexandra Blancke
Hentzschel, Franziska
Achcar, Fiona
Bertuccini, Lucia
Marti, Matthias
author_facet Ngotho, Priscilla
Soares, Alexandra Blancke
Hentzschel, Franziska
Achcar, Fiona
Bertuccini, Lucia
Marti, Matthias
author_sort Ngotho, Priscilla
collection PubMed
description Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito vector. They are present at low levels in blood circulation and significant knowledge gaps exist in their biology. Recent reductions in the global malaria burden have brought the possibility of elimination and eradication, with renewed focus on malaria transmission biology as a basis for interventions. This review discusses recent insights into gametocyte biology in the major human malaria parasite, Plasmodium falciparum and related species.
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spelling pubmed-66068492019-07-09 Revisiting gametocyte biology in malaria parasites Ngotho, Priscilla Soares, Alexandra Blancke Hentzschel, Franziska Achcar, Fiona Bertuccini, Lucia Marti, Matthias FEMS Microbiol Rev Review Article Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito vector. They are present at low levels in blood circulation and significant knowledge gaps exist in their biology. Recent reductions in the global malaria burden have brought the possibility of elimination and eradication, with renewed focus on malaria transmission biology as a basis for interventions. This review discusses recent insights into gametocyte biology in the major human malaria parasite, Plasmodium falciparum and related species. Oxford University Press 2019-04-09 /pmc/articles/PMC6606849/ /pubmed/31220244 http://dx.doi.org/10.1093/femsre/fuz010 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of FEMS. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ngotho, Priscilla
Soares, Alexandra Blancke
Hentzschel, Franziska
Achcar, Fiona
Bertuccini, Lucia
Marti, Matthias
Revisiting gametocyte biology in malaria parasites
title Revisiting gametocyte biology in malaria parasites
title_full Revisiting gametocyte biology in malaria parasites
title_fullStr Revisiting gametocyte biology in malaria parasites
title_full_unstemmed Revisiting gametocyte biology in malaria parasites
title_short Revisiting gametocyte biology in malaria parasites
title_sort revisiting gametocyte biology in malaria parasites
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606849/
https://www.ncbi.nlm.nih.gov/pubmed/31220244
http://dx.doi.org/10.1093/femsre/fuz010
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