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Targeting Mybbp1a suppresses HCC progression via inhibiting IGF1/AKT pathway by CpG islands hypo-methylation dependent promotion of IGFBP5

BACKGROUND: Myb-binding protein 1A (Mybbp1a) is a nucleolar protein that can regulate rRNA metabolism, the stress response and carcinogenesis. However, the function of Mybbp1a in the progression of hepatocellular carcinoma (HCC) is unclear. We aimed to determine the role of Mybbp1a in HCC and the un...

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Detalles Bibliográficos
Autores principales:	Weng, Xiaoyu, Wu, Jingbang, Lv, Zhen, Peng, Chuanhui, Chen, Junru, Zhang, Cheng, He, Bin, Tong, Rongliang, Hu, Wendi, Ding, Chaofeng, Cao, Linping, Chen, Diyu, Wu, Jian, Zheng, Shusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606930/ https://www.ncbi.nlm.nih.gov/pubmed/31109829 http://dx.doi.org/10.1016/j.ebiom.2019.05.029

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