Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma

Neurotrophins are critically involved in regulating normal neural development and plasticity. Brain-derived neurotrophic factor (BDNF), a neurotrophin that acts by binding to the tropomyosin receptor kinase B (TrkB) receptor, has also been implicated in the progression of several types of cancer. Ho...

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Detalles Bibliográficos
Autores principales: Thomaz, Amanda, Pinheiro, Kelly de Vargas, Souza, Bárbara Kunzler, Gregianin, Lauro, Brunetto, Algemir L., Brunetto, André T., de Farias, Caroline Brunetto, Jaeger, Mariane da Cunha, Ramaswamy, Vijay, Nör, Carolina, Taylor, Michael D., Roesler, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606946/
https://www.ncbi.nlm.nih.gov/pubmed/31297057
http://dx.doi.org/10.3389/fphar.2019.00698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606946/
https://www.ncbi.nlm.nih.gov/pubmed/31297057
http://dx.doi.org/10.3389/fphar.2019.00698

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