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Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma
Neurotrophins are critically involved in regulating normal neural development and plasticity. Brain-derived neurotrophic factor (BDNF), a neurotrophin that acts by binding to the tropomyosin receptor kinase B (TrkB) receptor, has also been implicated in the progression of several types of cancer. Ho...
Autores principales: | Thomaz, Amanda, Pinheiro, Kelly de Vargas, Souza, Bárbara Kunzler, Gregianin, Lauro, Brunetto, Algemir L., Brunetto, André T., de Farias, Caroline Brunetto, Jaeger, Mariane da Cunha, Ramaswamy, Vijay, Nör, Carolina, Taylor, Michael D., Roesler, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606946/ https://www.ncbi.nlm.nih.gov/pubmed/31297057 http://dx.doi.org/10.3389/fphar.2019.00698 |
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