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CDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock

All vertebrates share a segmented body axis. Segments form from the rostral end of the presomitic mesoderm (PSM) with a periodicity that is regulated by the segmentation clock. The segmentation clock is a molecular oscillator that exhibits dynamic clock gene expression across the PSM with a periodic...

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Detalles Bibliográficos
Autores principales: Carrieri, Francesca Anna, Murray, Philip J, Ditsova, Dimitrinka, Ferris, Margaret Ashley, Davies, Paul, Dale, Jacqueline Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607002/
https://www.ncbi.nlm.nih.gov/pubmed/31267714
http://dx.doi.org/10.15252/embr.201846436