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A novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: Short-term results of a pilot study

PURPOSE: To describe and evaluate the efficacy of the slit-integration method in the prevention of ring recurrence after graft substitution urethroplasty. MATERIALS AND METHODS: This was a pilot study of selected patients with urethral stricture disease who required urethroplasty from January 2016 t...

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Autores principales: Ajape, Abdulwahab Akanbi, Kuranga, Sulyman Alege, Olanipekun, Hamid Babajide, Mohammed, Taofiq Olayinka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Urological Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607076/
https://www.ncbi.nlm.nih.gov/pubmed/31294142
http://dx.doi.org/10.4111/icu.2019.60.4.319
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author Ajape, Abdulwahab Akanbi
Kuranga, Sulyman Alege
Olanipekun, Hamid Babajide
Mohammed, Taofiq Olayinka
author_facet Ajape, Abdulwahab Akanbi
Kuranga, Sulyman Alege
Olanipekun, Hamid Babajide
Mohammed, Taofiq Olayinka
author_sort Ajape, Abdulwahab Akanbi
collection PubMed
description PURPOSE: To describe and evaluate the efficacy of the slit-integration method in the prevention of ring recurrence after graft substitution urethroplasty. MATERIALS AND METHODS: This was a pilot study of selected patients with urethral stricture disease who required urethroplasty from January 2016 to December 2018. Patients were recruited into the study after they granted informed consent about the procedure. RESULTS: A total of eight patients were involved in this pilot study. The mean age (±standard deviation, SD) of the patients and the mean stricture length (±SD) were 44.25 (±11.07) years and 3.88 (±1.25) cm, respectively. The peno-bulbar region was the most frequently involved. The majority of the patients, 7 of 8 patients, underwent buccal mucosal graft repair with a mean graft length of 5.88 cm (range, 4–8 cm). There was leak during pericatheter urethrography in one patient. The mean (±SD) urethral calibers of the distal and proximal urethral anastomotic sites following urethroplasty were 26.00 (±1.85) and 25.25 (±1.83) at 1 week after removal of the urethral catheter stent and 27.75 (±0.71) and 27.75 (±0.71) at 12 months postoperatively, respectively. The mean maximum flow rate (±SD) at the 6- and 12-month follow-up was 20.25 (±1.83) and 21.88 (±1.73) mL/s, respectively. CONCLUSIONS: A slit-graft appropriately quilted into the corresponding urethrotomy incisions at the proximal and distal summit of the urethral stricture segments appears to mitigate the occurrence of ring contracture after urethroplasty. A randomized controlled trial of this technique with additional outcome assessment will be required to validate this observation.
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spelling pubmed-66070762019-07-10 A novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: Short-term results of a pilot study Ajape, Abdulwahab Akanbi Kuranga, Sulyman Alege Olanipekun, Hamid Babajide Mohammed, Taofiq Olayinka Investig Clin Urol Innovations in Urology PURPOSE: To describe and evaluate the efficacy of the slit-integration method in the prevention of ring recurrence after graft substitution urethroplasty. MATERIALS AND METHODS: This was a pilot study of selected patients with urethral stricture disease who required urethroplasty from January 2016 to December 2018. Patients were recruited into the study after they granted informed consent about the procedure. RESULTS: A total of eight patients were involved in this pilot study. The mean age (±standard deviation, SD) of the patients and the mean stricture length (±SD) were 44.25 (±11.07) years and 3.88 (±1.25) cm, respectively. The peno-bulbar region was the most frequently involved. The majority of the patients, 7 of 8 patients, underwent buccal mucosal graft repair with a mean graft length of 5.88 cm (range, 4–8 cm). There was leak during pericatheter urethrography in one patient. The mean (±SD) urethral calibers of the distal and proximal urethral anastomotic sites following urethroplasty were 26.00 (±1.85) and 25.25 (±1.83) at 1 week after removal of the urethral catheter stent and 27.75 (±0.71) and 27.75 (±0.71) at 12 months postoperatively, respectively. The mean maximum flow rate (±SD) at the 6- and 12-month follow-up was 20.25 (±1.83) and 21.88 (±1.73) mL/s, respectively. CONCLUSIONS: A slit-graft appropriately quilted into the corresponding urethrotomy incisions at the proximal and distal summit of the urethral stricture segments appears to mitigate the occurrence of ring contracture after urethroplasty. A randomized controlled trial of this technique with additional outcome assessment will be required to validate this observation. The Korean Urological Association 2019-07 2019-06-29 /pmc/articles/PMC6607076/ /pubmed/31294142 http://dx.doi.org/10.4111/icu.2019.60.4.319 Text en © The Korean Urological Association, 2019 http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Innovations in Urology
Ajape, Abdulwahab Akanbi
Kuranga, Sulyman Alege
Olanipekun, Hamid Babajide
Mohammed, Taofiq Olayinka
A novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: Short-term results of a pilot study
title A novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: Short-term results of a pilot study
title_full A novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: Short-term results of a pilot study
title_fullStr A novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: Short-term results of a pilot study
title_full_unstemmed A novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: Short-term results of a pilot study
title_short A novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: Short-term results of a pilot study
title_sort novel slit-integration method of graft urethroplasty in the prevention of ring recurrence: short-term results of a pilot study
topic Innovations in Urology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607076/
https://www.ncbi.nlm.nih.gov/pubmed/31294142
http://dx.doi.org/10.4111/icu.2019.60.4.319
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