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Unlocking Nanocarriers for the Programmed Release of Antimalarial Drugs

A programmable release system with wide range of release profiles of the antimalarial artemisone (ART) from fibrous nanocarriers (NFN) is presented. This is achieved following a new paradigm of using ART‐loaded NFN in infusion system of hydrophobic drug eluting nanocarriers, adapted to clinical appl...

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Detalles Bibliográficos
Autores principales: Bagheri, Amir Reza, Agarwal, Seema, Golenser, Jacob, Greiner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607132/
https://www.ncbi.nlm.nih.gov/pubmed/31565264
http://dx.doi.org/10.1002/gch2.201600011
Descripción
Sumario:A programmable release system with wide range of release profiles of the antimalarial artemisone (ART) from fibrous nanocarriers (NFN) is presented. This is achieved following a new paradigm of using ART‐loaded NFN in infusion system of hydrophobic drug eluting nanocarriers, adapted to clinical applications. Very importantly, under these conditions ART did not degrade as it was observed in solution. [Image: see text]