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lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial-mesenchymal transition by forming a positive feedback loop with c-Myc

Homeobox A transcript at the distal tip (HOTTIP) is an oncogenic long non-coding RNA in cancer. The aim of the present study was to investigate the function and mechanism of HOTTIP in the aggressive behaviors of human osteosarcoma (OS) cells. Expression levels of HOTTIP and epithelial-mesenchymal tr...

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Detalles Bibliográficos
Autores principales: Tang, Yang, Ji, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607149/
https://www.ncbi.nlm.nih.gov/pubmed/31423232
http://dx.doi.org/10.3892/ol.2019.10463