Hydrophilic Small Molecules That Harness Transthyretin To Enhance the Safety and Efficacy of Targeted Chemotherapeutic Agents

[Image: see text] The hydrophobicity of many chemotherapeutic agents usually results in their nonselective passive distribution into healthy cells and organs causing collateral toxicity. Ligand-targeted drugs (LTDs) are a promising class of targeted anticancer agents. The hydrophilicity of the targe...

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Detalles Bibliográficos
Autores principales: Pal, Arindom, Albusairi, Wabel, Liu, Fang, Tuhin, Md Tariqul Haque, Miller, Mark, Liang, Dengpan, Joo, Hyun, Amin, Toufiq Ul, Wilson, Elizabeth A., Faridi, Jesika S., Park, Miki, Alhamadsheh, Mamoun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607395/
https://www.ncbi.nlm.nih.gov/pubmed/31136717
http://dx.doi.org/10.1021/acs.molpharmaceut.9b00432

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