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Conserved motifs in the CRISPR leader sequence control spacer acquisition levels in Type I-D CRISPR-Cas systems

Integrating short DNA fragments at the correct leader-repeat junction is key to successful CRISPR-Cas memory formation. The Cas1–2 proteins are responsible to carry out this process. However, the CRISPR adaptation process additionally requires a DNA element adjacent to the CRISPR array, called leade...

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Detalles Bibliográficos
Autores principales:	Kieper, Sebastian N, Almendros, Cristóbal, Brouns, Stan J J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Research Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607411/ https://www.ncbi.nlm.nih.gov/pubmed/31252430 http://dx.doi.org/10.1093/femsle/fnz129

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