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Large choroidal melanoma presenting as neovascular glaucoma

Choroidal melanoma is a relatively rare tumour with a poor prognosis, though it is the most common primary malignancy of the eye among adults. Choroidal melanoma has been reported to present as acute angle closure glaucoma, secondary glaucoma, chronic uveitis, cataract, and staphyloma. We report a c...

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Autores principales: Sahu, Sabin, Bhutia, Tshering Wangchuk, Shrestha, Varun, Singh, Sanjay Kumar, Puri, Lila Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607447/
https://www.ncbi.nlm.nih.gov/pubmed/31293875
http://dx.doi.org/10.3205/oc000108
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author Sahu, Sabin
Bhutia, Tshering Wangchuk
Shrestha, Varun
Singh, Sanjay Kumar
Puri, Lila Raj
author_facet Sahu, Sabin
Bhutia, Tshering Wangchuk
Shrestha, Varun
Singh, Sanjay Kumar
Puri, Lila Raj
author_sort Sahu, Sabin
collection PubMed
description Choroidal melanoma is a relatively rare tumour with a poor prognosis, though it is the most common primary malignancy of the eye among adults. Choroidal melanoma has been reported to present as acute angle closure glaucoma, secondary glaucoma, chronic uveitis, cataract, and staphyloma. We report a case of a28-year-old male presenting with features of neovascular glaucoma in the right eye and having initially been treated with anti-glaucoma medications. However, ultrasonography revealed a mushroom-shaped, elevated, solid lesion with low to moderate internal reflectivity and regular internal structure suggestive of choroidal melanoma. Histopathological examination along with the immunohistochemistry studies of the lesion following enucleation of the eye confirmed the diagnosis of malignant choroidal melanoma. We highlight with this case that large choroidal melanoma may rarely present with features of neovascular glaucoma. The etiology of neovascular glaucoma should be investigated carefully and a potentially life-threatening intraocular tumour should be excluded, although it is a rare presentation.
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spelling pubmed-66074472019-07-10 Large choroidal melanoma presenting as neovascular glaucoma Sahu, Sabin Bhutia, Tshering Wangchuk Shrestha, Varun Singh, Sanjay Kumar Puri, Lila Raj GMS Ophthalmol Cases Article Choroidal melanoma is a relatively rare tumour with a poor prognosis, though it is the most common primary malignancy of the eye among adults. Choroidal melanoma has been reported to present as acute angle closure glaucoma, secondary glaucoma, chronic uveitis, cataract, and staphyloma. We report a case of a28-year-old male presenting with features of neovascular glaucoma in the right eye and having initially been treated with anti-glaucoma medications. However, ultrasonography revealed a mushroom-shaped, elevated, solid lesion with low to moderate internal reflectivity and regular internal structure suggestive of choroidal melanoma. Histopathological examination along with the immunohistochemistry studies of the lesion following enucleation of the eye confirmed the diagnosis of malignant choroidal melanoma. We highlight with this case that large choroidal melanoma may rarely present with features of neovascular glaucoma. The etiology of neovascular glaucoma should be investigated carefully and a potentially life-threatening intraocular tumour should be excluded, although it is a rare presentation. German Medical Science GMS Publishing House 2019-05-31 /pmc/articles/PMC6607447/ /pubmed/31293875 http://dx.doi.org/10.3205/oc000108 Text en Copyright © 2019 Sahu et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sahu, Sabin
Bhutia, Tshering Wangchuk
Shrestha, Varun
Singh, Sanjay Kumar
Puri, Lila Raj
Large choroidal melanoma presenting as neovascular glaucoma
title Large choroidal melanoma presenting as neovascular glaucoma
title_full Large choroidal melanoma presenting as neovascular glaucoma
title_fullStr Large choroidal melanoma presenting as neovascular glaucoma
title_full_unstemmed Large choroidal melanoma presenting as neovascular glaucoma
title_short Large choroidal melanoma presenting as neovascular glaucoma
title_sort large choroidal melanoma presenting as neovascular glaucoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607447/
https://www.ncbi.nlm.nih.gov/pubmed/31293875
http://dx.doi.org/10.3205/oc000108
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