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Large choroidal melanoma presenting as neovascular glaucoma
Choroidal melanoma is a relatively rare tumour with a poor prognosis, though it is the most common primary malignancy of the eye among adults. Choroidal melanoma has been reported to present as acute angle closure glaucoma, secondary glaucoma, chronic uveitis, cataract, and staphyloma. We report a c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
German Medical Science GMS Publishing House
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607447/ https://www.ncbi.nlm.nih.gov/pubmed/31293875 http://dx.doi.org/10.3205/oc000108 |
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author | Sahu, Sabin Bhutia, Tshering Wangchuk Shrestha, Varun Singh, Sanjay Kumar Puri, Lila Raj |
author_facet | Sahu, Sabin Bhutia, Tshering Wangchuk Shrestha, Varun Singh, Sanjay Kumar Puri, Lila Raj |
author_sort | Sahu, Sabin |
collection | PubMed |
description | Choroidal melanoma is a relatively rare tumour with a poor prognosis, though it is the most common primary malignancy of the eye among adults. Choroidal melanoma has been reported to present as acute angle closure glaucoma, secondary glaucoma, chronic uveitis, cataract, and staphyloma. We report a case of a28-year-old male presenting with features of neovascular glaucoma in the right eye and having initially been treated with anti-glaucoma medications. However, ultrasonography revealed a mushroom-shaped, elevated, solid lesion with low to moderate internal reflectivity and regular internal structure suggestive of choroidal melanoma. Histopathological examination along with the immunohistochemistry studies of the lesion following enucleation of the eye confirmed the diagnosis of malignant choroidal melanoma. We highlight with this case that large choroidal melanoma may rarely present with features of neovascular glaucoma. The etiology of neovascular glaucoma should be investigated carefully and a potentially life-threatening intraocular tumour should be excluded, although it is a rare presentation. |
format | Online Article Text |
id | pubmed-6607447 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | German Medical Science GMS Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-66074472019-07-10 Large choroidal melanoma presenting as neovascular glaucoma Sahu, Sabin Bhutia, Tshering Wangchuk Shrestha, Varun Singh, Sanjay Kumar Puri, Lila Raj GMS Ophthalmol Cases Article Choroidal melanoma is a relatively rare tumour with a poor prognosis, though it is the most common primary malignancy of the eye among adults. Choroidal melanoma has been reported to present as acute angle closure glaucoma, secondary glaucoma, chronic uveitis, cataract, and staphyloma. We report a case of a28-year-old male presenting with features of neovascular glaucoma in the right eye and having initially been treated with anti-glaucoma medications. However, ultrasonography revealed a mushroom-shaped, elevated, solid lesion with low to moderate internal reflectivity and regular internal structure suggestive of choroidal melanoma. Histopathological examination along with the immunohistochemistry studies of the lesion following enucleation of the eye confirmed the diagnosis of malignant choroidal melanoma. We highlight with this case that large choroidal melanoma may rarely present with features of neovascular glaucoma. The etiology of neovascular glaucoma should be investigated carefully and a potentially life-threatening intraocular tumour should be excluded, although it is a rare presentation. German Medical Science GMS Publishing House 2019-05-31 /pmc/articles/PMC6607447/ /pubmed/31293875 http://dx.doi.org/10.3205/oc000108 Text en Copyright © 2019 Sahu et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Sahu, Sabin Bhutia, Tshering Wangchuk Shrestha, Varun Singh, Sanjay Kumar Puri, Lila Raj Large choroidal melanoma presenting as neovascular glaucoma |
title | Large choroidal melanoma presenting as neovascular glaucoma |
title_full | Large choroidal melanoma presenting as neovascular glaucoma |
title_fullStr | Large choroidal melanoma presenting as neovascular glaucoma |
title_full_unstemmed | Large choroidal melanoma presenting as neovascular glaucoma |
title_short | Large choroidal melanoma presenting as neovascular glaucoma |
title_sort | large choroidal melanoma presenting as neovascular glaucoma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607447/ https://www.ncbi.nlm.nih.gov/pubmed/31293875 http://dx.doi.org/10.3205/oc000108 |
work_keys_str_mv | AT sahusabin largechoroidalmelanomapresentingasneovascularglaucoma AT bhutiatsheringwangchuk largechoroidalmelanomapresentingasneovascularglaucoma AT shresthavarun largechoroidalmelanomapresentingasneovascularglaucoma AT singhsanjaykumar largechoroidalmelanomapresentingasneovascularglaucoma AT purililaraj largechoroidalmelanomapresentingasneovascularglaucoma |