Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019

We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Örebro County, Sweden. These Aptima Combo 2 assay-negative specimens were Aptima Chlamydia trachomatis (CT) assay positive and had the characteristic...

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Autores principales: Unemo, Magnus, Hansen, Marit, Hadad, Ronza, Lindroth, Ylva, Fredlund, Hans, Puolakkainen, Mirja, Sundqvist, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2019
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607738/
https://www.ncbi.nlm.nih.gov/pubmed/31266590
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.26.1900370
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author Unemo, Magnus
Hansen, Marit
Hadad, Ronza
Lindroth, Ylva
Fredlund, Hans
Puolakkainen, Mirja
Sundqvist, Martin
author_facet Unemo, Magnus
Hansen, Marit
Hadad, Ronza
Lindroth, Ylva
Fredlund, Hans
Puolakkainen, Mirja
Sundqvist, Martin
author_sort Unemo, Magnus
collection PubMed
description We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Örebro County, Sweden. These Aptima Combo 2 assay-negative specimens were Aptima Chlamydia trachomatis (CT) assay positive and had the characteristic C1515T mutation in the 23S rRNA gene. From 22 March to 31 May 2019, 1.3% (2/158) of the CT-positive cases in Örebro County were missed because of the F-nvCT. International awareness, investigations and actions are essential.
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spelling pubmed-66077382019-07-18 Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019 Unemo, Magnus Hansen, Marit Hadad, Ronza Lindroth, Ylva Fredlund, Hans Puolakkainen, Mirja Sundqvist, Martin Euro Surveill Rapid Communication We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Örebro County, Sweden. These Aptima Combo 2 assay-negative specimens were Aptima Chlamydia trachomatis (CT) assay positive and had the characteristic C1515T mutation in the 23S rRNA gene. From 22 March to 31 May 2019, 1.3% (2/158) of the CT-positive cases in Örebro County were missed because of the F-nvCT. International awareness, investigations and actions are essential. European Centre for Disease Prevention and Control (ECDC) 2019-06-27 /pmc/articles/PMC6607738/ /pubmed/31266590 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.26.1900370 Text en This article is copyright of the authors or their affiliated institutions, 2019. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Unemo, Magnus
Hansen, Marit
Hadad, Ronza
Lindroth, Ylva
Fredlund, Hans
Puolakkainen, Mirja
Sundqvist, Martin
Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019
title Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019
title_full Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019
title_fullStr Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019
title_full_unstemmed Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019
title_short Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019
title_sort finnish new variant of chlamydia trachomatis escaping detection in the aptima combo 2 assay also present in örebro county, sweden, may 2019
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607738/
https://www.ncbi.nlm.nih.gov/pubmed/31266590
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.26.1900370
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