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The Fluctuations of Leukocytes and Circulating Cytokines in Septic Humanized Mice Vary With Outcome
Sepsis remains a major challenge in translational research given its heterogeneous pathophysiology and the lack of specific therapeutics. The use of humanized mouse chimeras with transplanted human hematopoietic cells may improve the clinical relevance of pre-clinical studies. However, knowledge of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607920/ https://www.ncbi.nlm.nih.gov/pubmed/31297113 http://dx.doi.org/10.3389/fimmu.2019.01427 |