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Nanotechnology for the treatment of deep endometriosis: uptake of lipid core nanoparticles by LDL receptors in endometriotic foci
OBJECTIVE: Rapidly dividing cells in multiple types of cancer and inflammatory diseases undergo high low density lipoprotein (LDL) uptake for membrane synthesis, and coupling an LDL-like nanoemulsion, containing lipid nanoparticles (LDE) to a chemotherapeutic agent efficiently targets these cells wi...
Autores principales: | Bedin, Alessandra, Maranhão, Raul C, Tavares, Elaine R, Carvalho, Priscila O, Baracat, Edmund C, Podgaec, Sérgio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607935/ https://www.ncbi.nlm.nih.gov/pubmed/31291391 http://dx.doi.org/10.6061/clinics/2019/e989 |
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