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IL‐4 induces a suppressive IL‐10‐producing CD8(+) T cell population via a Cdkn2a‐dependent mechanism

CD8(+) T cells play an important role in immune regulation and effective immune responses against tumor cells, viral infection, and intracellular pathogens. In this report, using tiger or 10BiT mice, we defined a population of IL‐10‐producing CD8(+) T cells that were induced by IL‐4. These IL‐10(+)C...

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Detalles Bibliográficos
Autores principales: Zhao, Yapu, Zhao, Huiyuan, Sun, Yuehong, Hao, Jianlei, Qi, Xiaofei, Zhou, Xinglong, Wu, Zhenzhou, Wang, Puyue, Kaech, Susan M., Weaver, Casey T., Flavell, Richard A., Zhao, Liqing, Yao, Zhi, Yin, Zhinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607996/
https://www.ncbi.nlm.nih.gov/pubmed/23772040
http://dx.doi.org/10.1189/jlb.0213064

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