Long-Acting and Selective Oxytocin Peptide Analogs Show Antidiabetic and Antiobesity Effects in Male Mice

Oxytocin (OXT) has been shown to suppress appetite, induce weight loss, and improve glycemic control and lipid metabolism in several species, including humans, monkeys, and rodents. However, OXT’s short half-life in circulation and lack of receptor selectivity limit its application and efficacy. In...

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Detalles Bibliográficos
Autores principales: Snider, Brandy, Geiser, Andrea, Yu, Xiao-peng, Beebe, Emily Cathleen, Willency, Jill Amanda, Qing, Keyun, Guo, Lili, Lu, Jianliang, Wang, Xiaojun, Yang, Qian, Efanov, Alexander, Adams, Andrew Charles, Coskun, Tamer, Emmerson, Paul Joseph, Alsina-Fernandez, Jorge, Ai, Minrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608564/
https://www.ncbi.nlm.nih.gov/pubmed/31286109
http://dx.doi.org/10.1210/js.2019-00004

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