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Actin clearance promotes polarized dynein accumulation at the immunological synapse
Immunological synapse (IS) formation between a T cell and an antigen-presenting cell is accompanied by the reorientation of the T cell centrosome toward the interface. This polarization response is thought to enhance the specificity of T cell effector function by enabling the directional secretion o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608937/ https://www.ncbi.nlm.nih.gov/pubmed/31269031 http://dx.doi.org/10.1371/journal.pone.0210377 |