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DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program
The molecular mechanism controlling the zygotic genome activation (ZGA) in mammals remains poorly understood. The 2-cell (2C)-like cells spontaneously emerging from cultures of mouse embryonic stem cells (ESCs) share some key transcriptional and epigenetic programs with 2C-stage embryos. By studying...
Autores principales: | Yan, Yao-Long, Zhang, Chao, Hao, Jing, Wang, Xue-Lian, Ming, Jia, Mi, Li, Na, Jie, Hu, Xinli, Wang, Yangming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608977/ https://www.ncbi.nlm.nih.gov/pubmed/31226106 http://dx.doi.org/10.1371/journal.pbio.3000324 |
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