let-7 and miR-17 promote self-renewal and drive gefitinib resistance in non-small cell lung cancer

Epidermal growth factor receptor-tyrosinase kinase inhibitor (EGFR-TKI) resistance represents a major obstacle in the therapy of non-small cell lung cancer (NSCLC), and the underlying molecular mechanisms are unknown. In this study, it was found that let-7 family expression was downregulated and miR...

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Detalles Bibliográficos
Autores principales: Yin, Jun, Hu, Weimin, Pan, Lei, Fu, Wenfan, Dai, Lu, Jiang, Zeyong, Zhang, Feng, Zhao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609324/
https://www.ncbi.nlm.nih.gov/pubmed/31233201
http://dx.doi.org/10.3892/or.2019.7197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609324/
https://www.ncbi.nlm.nih.gov/pubmed/31233201
http://dx.doi.org/10.3892/or.2019.7197

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