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let-7 and miR-17 promote self-renewal and drive gefitinib resistance in non-small cell lung cancer
Epidermal growth factor receptor-tyrosinase kinase inhibitor (EGFR-TKI) resistance represents a major obstacle in the therapy of non-small cell lung cancer (NSCLC), and the underlying molecular mechanisms are unknown. In this study, it was found that let-7 family expression was downregulated and miR...
Autores principales: | Yin, Jun, Hu, Weimin, Pan, Lei, Fu, Wenfan, Dai, Lu, Jiang, Zeyong, Zhang, Feng, Zhao, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609324/ https://www.ncbi.nlm.nih.gov/pubmed/31233201 http://dx.doi.org/10.3892/or.2019.7197 |
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