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Low expression of WWC1, a tumor suppressor gene, is associated with aggressive breast cancer and poor survival outcome

The WW and C2 domain containing 1 (WWC1) gene encodes a protein named WWC1 (or KIBRA), which is involved in the Hippo signaling pathway. WWC1 is often lost in triple‐negative breast cancer and has been shown to suppress tumor metastasis. In this study, 470 breast cancer patients were recruited and W...

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Detalles Bibliográficos
Autores principales: Wang, Zhanwei, Katsaros, Dionyssios, Biglia, Nicoletta, Shen, Yi, Fu, Yuanyuan, Tiirikainen, Maarit, Yu, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609559/
https://www.ncbi.nlm.nih.gov/pubmed/31102318
http://dx.doi.org/10.1002/2211-5463.12659