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A new split‐luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation
The expense and time required for in vivo reproductive and developmental toxicity studies have driven the development of in vitro alternatives. Here, we used a new in vitro split luciferase‐based assay to screen a library of 177 toxicants for inhibitors of apoptosome formation. The apoptosome contai...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609562/ https://www.ncbi.nlm.nih.gov/pubmed/31033240 http://dx.doi.org/10.1002/2211-5463.12646 |