Data for isolation and properties analysis of diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide

This article presents new data on the properties of the diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotides d(TpCp*A) [1,2]. The data include information on isolation, identification, treatment with snake venom phosphodiesterase and structural analysis by 1D and 2D NMR s...

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Detalles Bibliográficos
Autores principales: Lomzov, Alexander A., Kupryushkin, Maxim S., Shernyukov, Andrey V., Nekrasov, Mikhail D., Dovydenko, Ilya S., Stetsenko, Dmitry A., Pyshnyi, Dmitrii V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609727/
https://www.ncbi.nlm.nih.gov/pubmed/31312699
http://dx.doi.org/10.1016/j.dib.2019.104148
Descripción
Sumario:This article presents new data on the properties of the diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotides d(TpCp*A) [1,2]. The data include information on isolation, identification, treatment with snake venom phosphodiesterase and structural analysis by 1D and 2D NMR spectroscopy and restrained molecular dynamics analysis. The data can be used for preparation, analysis, application of phosphoryl guanidine oligonucleotide and for development of new nucleic acids derivatives. This data article is associated with the manuscript titled “Diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide: isolation and properties” [1].

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