Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli

Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant Escherichia coli strains. All of E. coli isolates co-pr...

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Autores principales: Ahn, Kwangjin, Hwang, Gyu Yel, Kim, Young Keun, Kim, Hyo Youl, Jeong, Hye Ran, Hong, Jun Sung, Uh, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Infectious Diseases and Korean Society for Chemotherapy 2019
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609740/
https://www.ncbi.nlm.nih.gov/pubmed/31270997
http://dx.doi.org/10.3947/ic.2019.51.2.177
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author Ahn, Kwangjin
Hwang, Gyu Yel
Kim, Young Keun
Kim, Hyo Youl
Jeong, Hye Ran
Hong, Jun Sung
Uh, Young
author_facet Ahn, Kwangjin
Hwang, Gyu Yel
Kim, Young Keun
Kim, Hyo Youl
Jeong, Hye Ran
Hong, Jun Sung
Uh, Young
author_sort Ahn, Kwangjin
collection PubMed
description Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant Escherichia coli strains. All of E. coli isolates co-produced bla(NDM-5) and bla(OXA-181) carbapenemase genes and shared ≥88% clonal relatedness on the basis of a cladistic calculation of the distribution of pulsed-field gel electrophoresis patterns. Rapid detection of CPE is one of the most important factors to prevent CPE dissemination because it takes long time for CPE to become negative.
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spelling pubmed-66097402019-07-11 Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli Ahn, Kwangjin Hwang, Gyu Yel Kim, Young Keun Kim, Hyo Youl Jeong, Hye Ran Hong, Jun Sung Uh, Young Infect Chemother Brief Communication Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant Escherichia coli strains. All of E. coli isolates co-produced bla(NDM-5) and bla(OXA-181) carbapenemase genes and shared ≥88% clonal relatedness on the basis of a cladistic calculation of the distribution of pulsed-field gel electrophoresis patterns. Rapid detection of CPE is one of the most important factors to prevent CPE dissemination because it takes long time for CPE to become negative. The Korean Society of Infectious Diseases and Korean Society for Chemotherapy 2019-06 2019-06-10 /pmc/articles/PMC6609740/ /pubmed/31270997 http://dx.doi.org/10.3947/ic.2019.51.2.177 Text en Copyright © 2019 by The Korean Society of Infectious Diseases and Korean Society for Antimicrobial Therapy https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Ahn, Kwangjin
Hwang, Gyu Yel
Kim, Young Keun
Kim, Hyo Youl
Jeong, Hye Ran
Hong, Jun Sung
Uh, Young
Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli
title Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli
title_full Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli
title_fullStr Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli
title_full_unstemmed Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli
title_short Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli
title_sort nosocomial outbreak caused by ndm-5 and oxa-181 carbapenemase co-producing escherichia coli
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609740/
https://www.ncbi.nlm.nih.gov/pubmed/31270997
http://dx.doi.org/10.3947/ic.2019.51.2.177
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