Cargando…

Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation

The tumor suppressor activity of maspin (mammary serine protease inhibitor) has been associated with its nuclear localization. In this study we explore the regulation of maspin nuclear translocation. An in vitro nuclear import assay suggested that maspin can passively enter the nucleus. However, in ...

Descripción completa

Detalles Bibliográficos
Autores principales: Reina, Jeffrey, Zhou, Lixin, Fontes, Marcos R. M., Panté, Nelly, Cella, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609763/
https://www.ncbi.nlm.nih.gov/pubmed/31144423
http://dx.doi.org/10.1002/2211-5463.12626