Comparison of an ordinal endpoint to time-to-event, longitudinal, and binary endpoints for use in evaluating treatments for severe influenza requiring hospitalization

BACKGROUND/AIMS: The Food and Drug Administration recommends research into developing well-defined and reliable endpoints to evaluate treatments for severe influenza requiring hospitalization. A novel 6-category ordinal endpoint of patient health status after 7 days that ranges from death to hospita...

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Detalles Bibliográficos
Autores principales: Peterson, Ross L., Vock, David M., Babiker, Abdel, Powers, John H., Hunsberger, Sally, Angus, Brian, Paez, Armando, Neaton, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609815/
https://www.ncbi.nlm.nih.gov/pubmed/31312748
http://dx.doi.org/10.1016/j.conctc.2019.100401

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