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Accurate identification of clinically important Acinetobacter spp.: an update
Acinetobacter species have emerged as one of the most clinically important pathogens. The phenotypic techniques which are currently available are insufficient in accurately identifying and differentiating the closely related and clinically important Acinetobacter species. Here, we discuss the advant...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609899/ https://www.ncbi.nlm.nih.gov/pubmed/31285840 http://dx.doi.org/10.2144/fsoa-2018-0127 |
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author | Vijayakumar, Saranya Biswas, Indranil Veeraraghavan, Balaji |
author_facet | Vijayakumar, Saranya Biswas, Indranil Veeraraghavan, Balaji |
author_sort | Vijayakumar, Saranya |
collection | PubMed |
description | Acinetobacter species have emerged as one of the most clinically important pathogens. The phenotypic techniques which are currently available are insufficient in accurately identifying and differentiating the closely related and clinically important Acinetobacter species. Here, we discuss the advantages and limitations of the conventional phenotypic methods, automated identification systems, molecular methods and MALDI-TOF in the precise identification and differentiation of Acinetobacter species. More specifically, several species of this genus are increasingly reported to be of high clinical importance. Molecular characterization such as of bla(OXA-51)-like PCR together with rpoB sequencing has high discriminatory power over the conventional methods for Acinetobacter species identification, especially within the Acinetobacter calcoaceticus–Acinetobacter baumannii complex. |
format | Online Article Text |
id | pubmed-6609899 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Future Science Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-66098992019-07-08 Accurate identification of clinically important Acinetobacter spp.: an update Vijayakumar, Saranya Biswas, Indranil Veeraraghavan, Balaji Future Sci OA Review Acinetobacter species have emerged as one of the most clinically important pathogens. The phenotypic techniques which are currently available are insufficient in accurately identifying and differentiating the closely related and clinically important Acinetobacter species. Here, we discuss the advantages and limitations of the conventional phenotypic methods, automated identification systems, molecular methods and MALDI-TOF in the precise identification and differentiation of Acinetobacter species. More specifically, several species of this genus are increasingly reported to be of high clinical importance. Molecular characterization such as of bla(OXA-51)-like PCR together with rpoB sequencing has high discriminatory power over the conventional methods for Acinetobacter species identification, especially within the Acinetobacter calcoaceticus–Acinetobacter baumannii complex. Future Science Ltd 2019-06-27 /pmc/articles/PMC6609899/ /pubmed/31285840 http://dx.doi.org/10.2144/fsoa-2018-0127 Text en © 2019 Veeraraghavan Balaji This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Review Vijayakumar, Saranya Biswas, Indranil Veeraraghavan, Balaji Accurate identification of clinically important Acinetobacter spp.: an update |
title | Accurate identification of clinically important Acinetobacter spp.: an update |
title_full | Accurate identification of clinically important Acinetobacter spp.: an update |
title_fullStr | Accurate identification of clinically important Acinetobacter spp.: an update |
title_full_unstemmed | Accurate identification of clinically important Acinetobacter spp.: an update |
title_short | Accurate identification of clinically important Acinetobacter spp.: an update |
title_sort | accurate identification of clinically important acinetobacter spp.: an update |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609899/ https://www.ncbi.nlm.nih.gov/pubmed/31285840 http://dx.doi.org/10.2144/fsoa-2018-0127 |
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