Cargando…
DNA-PKcs inhibitor increases the sensitivity of gastric cancer cells to radiotherapy
Gastric cancer (GC) is a severe public health problem worldwide, particularly in China. Radiotherapy is the main locoregional treatment for various types of unresectable tumor, including GC. However, many patients fail to respond to radiotherapy due to the intrinsic radioresistance of cancer cells....
Autores principales: | Geng, Wei, Tian, Dalong, Wang, Qiang, Shan, Shunlin, Zhou, Jianwei, Xu, Wenxia, Shan, Husheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610038/ https://www.ncbi.nlm.nih.gov/pubmed/31173270 http://dx.doi.org/10.3892/or.2019.7187 |
Ejemplares similares
-
KU-0060648 inhibits hepatocellular carcinoma cells through DNA-PKcs-dependent and DNA-PKcs-independent mechanisms
por: Chen, Min-Bin, et al.
Publicado: (2016) -
Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs
por: Liang, Shikang, et al.
Publicado: (2022) -
Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy
por: Willoughby, Catherine E., et al.
Publicado: (2019) -
DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo
por: Reuvers, Thom G.A., et al.
Publicado: (2023) -
ATM, ATR and DNA-PKcs kinases—the lessons from the mouse models: inhibition ≠ deletion
por: Menolfi, Demis, et al.
Publicado: (2020)