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Cucurbitacin E inhibits the Yes-associated protein signaling pathway and suppresses brain metastasis of human non-small cell lung cancer in a murine model
Human non-small cell lung cancer (NSCLC) is associated with an extremely poor prognosis especially for the 40% of patients who develop brain metastasis, and few treatment strategies exist. Cucurbitacin E (CuE), an oxygenated tetracyclic triterpenoid isolated from plants particularly of the family Cu...
Autores principales: | Hsu, Ping-Chih, Tian, Bo, Yang, Yi-Lin, Wang, Yu-Cheng, Liu, Shu, Urisman, Anatoly, Yang, Cheng-Ta, Xu, Zhidong, Jablons, David M., You, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610039/ https://www.ncbi.nlm.nih.gov/pubmed/31233205 http://dx.doi.org/10.3892/or.2019.7207 |
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