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Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation

5-lipoxygenase (5-LOX) is a non-heme iron-containing dioxygenase expressed in immune cells that catalyzes the two initial steps in the biosynthesis of leukotrienes. It is well known that 5-LOX activation in innate immunity cells is related to different iron-associated pro-inflammatory disorders, inc...

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Detalles Bibliográficos
Autores principales:	Dufrusine, Beatrice, Di Francesco, Andrea, Oddi, Sergio, Scipioni, Lucia, Angelucci, Clotilde Beatrice, D'Addario, Claudio, Serafini, Mauro, Häfner, Ann-Kathrin, Steinhilber, Dieter, Maccarrone, Mauro, Dainese, Enrico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610208/ https://www.ncbi.nlm.nih.gov/pubmed/31316498 http://dx.doi.org/10.3389/fimmu.2019.01347

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