Alkylative Ring-Opening of Bicyclic Aziridinium Ion and Its Application for Alkaloid Synthesis

Alkylative ring-opening of bicyclic aziridinium ion generated from 4-hydroxybutylaziridine with organocopper reagent was achieved successfully to afford 2-alkylsubstituted piperidine in high or moderate yield. This method allowed carbon-carbon bond formation of “non-activated” aziridine via aziridin...

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Detalles Bibliográficos
Autores principales: Yadav, Nagendra Nath, Lee, Young-Gun, Srivastava, Nikhil, Ha, Hyun-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610304/
https://www.ncbi.nlm.nih.gov/pubmed/31316970
http://dx.doi.org/10.3389/fchem.2019.00460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610304/
https://www.ncbi.nlm.nih.gov/pubmed/31316970
http://dx.doi.org/10.3389/fchem.2019.00460

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