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Alkylative Ring-Opening of Bicyclic Aziridinium Ion and Its Application for Alkaloid Synthesis
Alkylative ring-opening of bicyclic aziridinium ion generated from 4-hydroxybutylaziridine with organocopper reagent was achieved successfully to afford 2-alkylsubstituted piperidine in high or moderate yield. This method allowed carbon-carbon bond formation of “non-activated” aziridine via aziridin...
Autores principales: | Yadav, Nagendra Nath, Lee, Young-Gun, Srivastava, Nikhil, Ha, Hyun-Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610304/ https://www.ncbi.nlm.nih.gov/pubmed/31316970 http://dx.doi.org/10.3389/fchem.2019.00460 |
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