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Residue-specific identification of phase separation hot spots of Alzheimer's-related protein tau

Liquid–liquid phase separation (LLPS) of proteins enables the formation of non-membrane-bound organelles in cells and is associated with cancer and neurodegeneration. Little is known however about the structure and dynamics of proteins in LLPS conditions, because of the polymorphic nature of liquid-...

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Detalles Bibliográficos
Autores principales:	Ambadipudi, Susmitha, Reddy, Jithender G., Biernat, Jacek, Mandelkow, Eckhard, Zweckstetter, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610569/ https://www.ncbi.nlm.nih.gov/pubmed/31341602 http://dx.doi.org/10.1039/c9sc00531e

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