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Recruitment, Retainment, and Biomarkers of Response; A Pilot Trial of Lithium in Humans With Mild Cognitive Impairment

Lithium has been used for decades to treat Bipolar Disorder. Some of its therapeutic benefits may be through inhibition of Glycogen Synthase Kinase (GSK)-3. Enhanced GSK3 activity associates with development of Alzheimer’s disease (AD), therefore lithium is a currently used therapeutic with potentia...

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Detalles Bibliográficos
Autores principales: Duthie, Ashleigh, van Aalten, Lidy, MacDonald, Cara, McNeilly, Alison, Gallagher, Jennifer, Geddes, John, Lovestone, Simon, Sutherland, Calum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610581/
https://www.ncbi.nlm.nih.gov/pubmed/31316348
http://dx.doi.org/10.3389/fnmol.2019.00163