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Overexpression of Smac by an Armed Vesicular Stomatitis Virus Overcomes Tumor Resistance

Despite reports of successful clinical cases, many tumors appear to resist infection by oncolytic viruses (OVs). To circumvent this problem, an armed vesicular stomatitis virus was constructed by inserting a transgene to express Smac/DIABLO during virus infection (VSV-S). Endogenous Smac in HeLa cel...

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Detalles Bibliográficos
Autores principales:	Li, Weike, Turaga, Ravi Chakra, Li, Xin, Sharma, Malvika, Enadi, Zahra, Dunham Tompkins, Sydney Nicole, Hardy, Kyle Christian, Mishra, Falguni, Tsao, Jun, Liu, Zhi-ren, Fan, Daping, Luo, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610632/ https://www.ncbi.nlm.nih.gov/pubmed/31312717 http://dx.doi.org/10.1016/j.omto.2019.05.006

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