Cargando…

Multi-centre technical evaluation of the radiation-induced lymphocyte apoptosis assay as a predictive test for radiotherapy toxicity

Predicting which patients will develop adverse reactions to radiotherapy is important for personalised treatment. Prediction will require an algorithm or nomogram combining clinical and biological data. The radiation-induced lymphocyte apoptosis (RILA) assay is the leading candidate as a biological...

Descripción completa

Detalles Bibliográficos
Autores principales:	Talbot, Christopher J., Veldwijk, Marlon R., Azria, David, Batini, Chiara, Bierbaum, Miriam, Brengues, Muriel, Chang-Claude, Jenny, Johnson, Kerstie, Keller, Anke, Smith, Sheila, Sperk, Elena, Symonds, R. Paul, Wenz, Frederik, West, Catharine M.L., Herskind, Carsten, Bourgier, Celine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610684/ https://www.ncbi.nlm.nih.gov/pubmed/31341970 http://dx.doi.org/10.1016/j.ctro.2019.06.001

Ejemplares similares

One Size Fits All: Does the Dogma Stand in Radiation Oncology?
por: Azria, David, et al.
Publicado: (2016)

Personalizing Breast Cancer Irradiation Using Biology: From Bench to the Accelerator
por: Azria, David, et al.
Publicado: (2018)

The Biological Effect of Large Single Doses: A Possible Role for Non-Targeted Effects in Cell Inactivation
por: Veldwijk, Marlon R., et al.
Publicado: (2014)

Biology of high single doses of IORT: RBE, 5 R’s, and other biological aspects
por: Herskind, Carsten, et al.
Publicado: (2017)

Quantitative proteomic analysis reveals AK2 as potential biomarker for late normal tissue radiotoxicity
por: Lacombe, Jérôme, et al.
Publicado: (2019)

Improving Patients’ Life Quality after Radiotherapy Treatment by Predicting Late Toxicities
por: Lapierre, Ariane, et al.
Publicado: (2022)

Intracellular Delivery of Doxorubicin by Iron Oxide-Based Nano-Constructs Increases Clonogenic Inactivation of Ionizing Radiation in HeLa Cells
por: Popescu, Roxana Cristina, et al.
Publicado: (2021)

TGF-β1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT)
por: Scherer, Sandra D., et al.
Publicado: (2016)

INTRAGO: intraoperative radiotherapy in glioblastoma multiforme – a Phase I/II dose escalation study
por: Giordano, Frank A, et al.
Publicado: (2014)

Targeting Cell Cycle Checkpoint Kinases to Overcome Intrinsic Radioresistance in Brain Tumor Cells
por: Vlatkovic, Tijana, et al.
Publicado: (2022)

Immunotherapy Combined with Large Fractions of Radiotherapy: Stereotactic Radiosurgery for Brain Metastases—Implications for Intraoperative Radiotherapy after Resection
por: Herskind, Carsten, et al.
Publicado: (2017)

Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization
por: Maier, Patrick, et al.
Publicado: (2016)

Multidisciplinary approach of early breast cancer: The biology applied to radiation oncology
por: Bourgier, Céline, et al.
Publicado: (2010)

Targeting the DNA Damage Response and DNA Repair Pathways to Enhance Radiosensitivity in Colorectal Cancer
por: Deng, Siyao, et al.
Publicado: (2022)

Development of a method for generating SNP interaction-aware polygenic risk scores for radiotherapy toxicity
por: Franco, Nicola Rares, et al.
Publicado: (2021)

Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis
por: Weigel, Christoph, et al.
Publicado: (2016)

Treatment time and circadian genotype interact to influence radiotherapy side-effects. A prospective European validation study using the REQUITE cohort
por: Webb, Adam J., et al.
Publicado: (2022)

Gene Expression Profiles Reveal Extracellular Matrix and Inflammatory Signaling in Radiation-Induced Premature Differentiation of Human Fibroblast in vitro
por: Herskind, Carsten, et al.
Publicado: (2021)

The HIV-derived protein Vpr(52-96) has anti-glioma activity in vitro and in vivo
por: Kübler, Jens, et al.
Publicado: (2016)

High weekly integral dose and larger fraction size increase risk of fatigue and worsening of functional outcomes following radiotherapy for localized prostate cancer
por: Joseph, Nuradh, et al.
Publicado: (2022)

A cohort analysis to identify eligible patients for intraoperative radiotherapy (IORT) of early breast cancer
por: Sperk, Elena, et al.
Publicado: (2014)

Radiation-induced malignancies after intensity-modulated versus conventional mediastinal radiotherapy in a small animal model
por: Gomarteli, Kaga, et al.
Publicado: (2019)

Predicting response to neoadjuvant chemoradiotherapy in rectal cancer: from biomarkers to tumor models
por: Li, Moying, et al.
Publicado: (2022)

Different meaning of the mean heart dose between 3D-CRT and IMRT for breast cancer radiotherapy
por: Prunaretty, Jessica, et al.
Publicado: (2023)

TARGIT-E(lderly)—Prospective phase II study of intraoperative radiotherapy (IORT) in elderly patients with small breast cancer
por: Neumaier, Christian, et al.
Publicado: (2012)

Long-term changes in blood counts after intraoperative radiotherapy for breast cancer—single center experience and review of the literature
por: Wersal, Cornelia, et al.
Publicado: (2019)

Can the risk of secondary cancer induction after breast conserving therapy be reduced using intraoperative radiotherapy (IORT) with low-energy x-rays?
por: Aziz, Muhammad Hammad, et al.
Publicado: (2011)

Robustness of Breast Margins with Volumetric Modulated Arc Therapy without a Six-Degrees-of-Freedom Couch: A Dosimetric Evaluation
por: Prunaretty, Jessica, et al.
Publicado: (2023)

Management of the Axilla in the Era of Breast Cancer Heterogeneity
por: de Meric de Bellefon, Maïlys, et al.
Publicado: (2018)

A Deep Learning Approach Validates Genetic Risk Factors for Late Toxicity After Prostate Cancer Radiotherapy in a REQUITE Multi-National Cohort
por: Massi, Michela Carlotta, et al.
Publicado: (2020)

Targeting the Post-Irradiation Tumor Microenvironment in Glioblastoma via Inhibition of CXCL12
por: Giordano, Frank A., et al.
Publicado: (2019)

Impact of adjuvant hormonotherapy on radiation-induced breast fibrosis according to the individual radiosensitivity: results of a multicenter prospective French trial
por: Bourgier, Céline, et al.
Publicado: (2018)

Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response
por: Liu, Chun-Shan, et al.
Publicado: (2021)

Feasibility study of adaptive radiotherapy with Ethos for breast cancer
por: Galand, Arthur, et al.
Publicado: (2023)

Application of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line
por: Stiefelhagen, Marius, et al.
Publicado: (2008)

Development and Optimization of a Machine-Learning Prediction Model for Acute Desquamation After Breast Radiation Therapy in the Multicenter REQUITE Cohort
por: Aldraimli, Mahmoud, et al.
Publicado: (2022)

Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era
por: Azria, David, et al.
Publicado: (2017)

Efficacy, safety, and feasibility of volumetric modulated arc therapy for synchronous bilateral breast cancer management
por: Quesada, Stanislas, et al.
Publicado: (2022)

Association of polymorphisms in TGFB1, XRCC1, XRCC3 genes and CD8 T-lymphocyte apoptosis with adverse effect of radiotherapy for prostate cancer
por: Mališić, Emina, et al.
Publicado: (2022)

Cardiac serum marker alterations after intraoperative radiotherapy with low-energy x-rays in early breast cancer as an indicator of possible cardiac toxicity
por: Stefanovic, Stefan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5ohaf7kut2rlfr2ag77k29lue3