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Modulation of chimeric antigen receptor surface expression by a small molecule switch

BACKGROUND: Engineered therapeutic cells have attracted a great deal of interest due to their potential applications in treating a wide range of diseases, including cancer and autoimmunity. Chimeric antigen receptor (CAR) T-cells are designed to detect and kill tumor cells that present a specific, p...

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Detalles Bibliográficos
Autores principales:	Juillerat, Alexandre, Tkach, Diane, Busser, Brian W., Temburni, Sonal, Valton, Julien, Duclert, Aymeric, Poirot, Laurent, Depil, Stéphane, Duchateau, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610870/ https://www.ncbi.nlm.nih.gov/pubmed/31269942 http://dx.doi.org/10.1186/s12896-019-0537-3

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