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Knockdown of YAP inhibits growth in Hep-2 laryngeal cancer cells via epithelial-mesenchymal transition and the Wnt/β-catenin pathway

BACKGROUND: Yes-associated protein (YAP) plays a crucial role in tumour development and it is the main effector of the Hippo signalling pathway. However, the mechanism underlying YAP downregulation in laryngeal cancer is still unclear. In our previous study, we found that YAP, compared with adjacent...

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Detalles Bibliográficos
Autores principales: Tang, Xiaomin, Sun, Yuxuan, Wan, Ganglun, Sun, Jiaqiang, Sun, Jingwu, Pan, Chunchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610877/
https://www.ncbi.nlm.nih.gov/pubmed/31269911
http://dx.doi.org/10.1186/s12885-019-5832-9