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Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure
BACKGROUND: The chemokine receptor CCR7, expressed on various immune cells, is associated with cell migration and lympho-node homing. Mice lacking Ccr7 are protected from diet-induced obesity and subsequent insulin resistance. We evaluated the mechanism underlying these protective effects from the s...
Autores principales: | Sano, Tomomi, Sanada, Taiki, Sotomaru, Yusuke, Shinjo, Takanori, Iwashita, Misaki, Yamashita, Akiko, Fukuda, Takao, Sanui, Terukazu, Asano, Tomoichiro, Kanematsu, Takashi, Nishimura, Fusanori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610939/ https://www.ncbi.nlm.nih.gov/pubmed/31312229 http://dx.doi.org/10.1186/s12986-019-0372-5 |
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