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Testicular Cancer mortality in Brazil: trends and predictions until 2030

BACKGROUND: Despite the fact that testicular cancer presents good prognosis, wide variations in mortality rates have been reported internationally. In Brazil, mortality trends and estimates have not been fully assessed. The objective of the study presented herein is to analyze the mortality trends f...

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Autores principales: Soares, Samara Carollyne Mafra, dos Santos, Katarina Márcia Rodrigues, de Morais Fernandes, Fabia Cheyenne Gomes, Barbosa, Isabelle Ribeiro, de Souza, Dyego Leandro Bezerra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611043/
https://www.ncbi.nlm.nih.gov/pubmed/31277621
http://dx.doi.org/10.1186/s12894-019-0487-z
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author Soares, Samara Carollyne Mafra
dos Santos, Katarina Márcia Rodrigues
de Morais Fernandes, Fabia Cheyenne Gomes
Barbosa, Isabelle Ribeiro
de Souza, Dyego Leandro Bezerra
author_facet Soares, Samara Carollyne Mafra
dos Santos, Katarina Márcia Rodrigues
de Morais Fernandes, Fabia Cheyenne Gomes
Barbosa, Isabelle Ribeiro
de Souza, Dyego Leandro Bezerra
author_sort Soares, Samara Carollyne Mafra
collection PubMed
description BACKGROUND: Despite the fact that testicular cancer presents good prognosis, wide variations in mortality rates have been reported internationally. In Brazil, mortality trends and estimates have not been fully assessed. The objective of the study presented herein is to analyze the mortality trends for testicular cancer in Brazil in the period 2001–2015 and calculate mortality predictions for the period 2016–2030. METHODS: This is a population-based ecological study that utilized information of the Mortality Information System, on testicular cancer-related deaths in Brazil. Mortality trends were analyzed by Joinpoint regression, and Nordpred was utilized for the calculation of predictions. RESULTS: The mortality rate for men, standardized to the world population, varied between 0.36/100,000 for the year 2001, to 0.41/100,000 for the year 2015. There was an increasing trend for Brazil (APC = 1.3% CI95% 0.6; 2.0) and the Southeast region (APC = 1.5% CI95%0.2; 2.7). When analyzing Brazilian data for the period 2016–2030, predictions indicate 2888 deaths due to testicular cancer, which corresponds to a 26.6% change when compared to the 2011–2015 period. This change is mostly explained by an increase in the risk of death (14.2%) when compared with modifications in the demographic structure (12.4%). CONCLUSIONS: Testicular cancer mortality in Brazil presents increasing trends, and until 2030 these rates continue to increase.
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spelling pubmed-66110432019-07-16 Testicular Cancer mortality in Brazil: trends and predictions until 2030 Soares, Samara Carollyne Mafra dos Santos, Katarina Márcia Rodrigues de Morais Fernandes, Fabia Cheyenne Gomes Barbosa, Isabelle Ribeiro de Souza, Dyego Leandro Bezerra BMC Urol Research Article BACKGROUND: Despite the fact that testicular cancer presents good prognosis, wide variations in mortality rates have been reported internationally. In Brazil, mortality trends and estimates have not been fully assessed. The objective of the study presented herein is to analyze the mortality trends for testicular cancer in Brazil in the period 2001–2015 and calculate mortality predictions for the period 2016–2030. METHODS: This is a population-based ecological study that utilized information of the Mortality Information System, on testicular cancer-related deaths in Brazil. Mortality trends were analyzed by Joinpoint regression, and Nordpred was utilized for the calculation of predictions. RESULTS: The mortality rate for men, standardized to the world population, varied between 0.36/100,000 for the year 2001, to 0.41/100,000 for the year 2015. There was an increasing trend for Brazil (APC = 1.3% CI95% 0.6; 2.0) and the Southeast region (APC = 1.5% CI95%0.2; 2.7). When analyzing Brazilian data for the period 2016–2030, predictions indicate 2888 deaths due to testicular cancer, which corresponds to a 26.6% change when compared to the 2011–2015 period. This change is mostly explained by an increase in the risk of death (14.2%) when compared with modifications in the demographic structure (12.4%). CONCLUSIONS: Testicular cancer mortality in Brazil presents increasing trends, and until 2030 these rates continue to increase. BioMed Central 2019-07-05 /pmc/articles/PMC6611043/ /pubmed/31277621 http://dx.doi.org/10.1186/s12894-019-0487-z Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Soares, Samara Carollyne Mafra
dos Santos, Katarina Márcia Rodrigues
de Morais Fernandes, Fabia Cheyenne Gomes
Barbosa, Isabelle Ribeiro
de Souza, Dyego Leandro Bezerra
Testicular Cancer mortality in Brazil: trends and predictions until 2030
title Testicular Cancer mortality in Brazil: trends and predictions until 2030
title_full Testicular Cancer mortality in Brazil: trends and predictions until 2030
title_fullStr Testicular Cancer mortality in Brazil: trends and predictions until 2030
title_full_unstemmed Testicular Cancer mortality in Brazil: trends and predictions until 2030
title_short Testicular Cancer mortality in Brazil: trends and predictions until 2030
title_sort testicular cancer mortality in brazil: trends and predictions until 2030
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611043/
https://www.ncbi.nlm.nih.gov/pubmed/31277621
http://dx.doi.org/10.1186/s12894-019-0487-z
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